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Arthur Zinn
Associate Professor
Center for Human Genetics
University Hospitals of Cleveland
1500 Lakeside (UH)
11100 Euclid Ave.
Cleveland, Oh 44106
Tel: (216) 844-5173
Fax: (216) 983-0221
E-mail: arthur.zinn@uhhospitals.org


About Arthur Zinn

Education:
1965 - 1969 Brandeis University, B.A. (cum laude, chemistry) 1969 - 1976 Case Western Reserve University, M.D. 1969 - 1977 Case Western Reserve University, Ph.D. (biochemistry) 1977 - 1979 University of Minnesota Hospitals, Pediatrics residency 1979 - 1982 Yale University, Human Genetics fellowship


Research

Academic appointments:
1982 - 1992 Assistant Professor of Pediatrics, Case Western Reserve University 1992 - Associate Professor of Pediatrics, Case Western Reserve University 1993 - Associate Professor of Genetics, Case Western Reserve University

Hospital appointments:
1982 - Full-time member of active staff, Rainbow Babies and Childrens Hospital of University Hospitals of Cleveland 1999 - Tod Children’s Hospital, Youngstown, OH

Honors and Awards:
1969 - 1976 Medical Scientist Training Program Award 1983 Frederick C. Robbins Award, March of Dimes, Northeast Ohio chapter 1985 International Travel Award, American Society of Human Genetics 1991 Department of Pediatrics Teaching Excellence Award

Licensure: 1982 - Ohio

Board certification:
1981 American Board of Medical Examiners 1982 American Board of Medical Genetics (Clinical) 1996 American Board of Medical Genetics (Clinical Biochemical)

Professional Service:
1991 - Medical Advisory Board, National Organic Acidemia
Association 1994 - Medical Advisory Board, Huntington Disease Society of America, Northeast Ohio Chapter

Journal reviewer:
American Journal of Human Genetics Clinical Pediatrics Human Molecular Genetics Journal of Biological Chemistry Journal of Clinical Investigation Journal of Pediatrics Neurology New England Journal of Medicine

National collaborative programs:
1991 - Register of Selected Inherited Metabolic Disorders 1991 - Value of Bone Marrow Transplantation for Storage Disorders 1994 - Director, Designated Gaucher Disease Treatment Center

Professional societies:
1982 - American Society of Human Genetics 1993 - Society for Inherited Metabolic Disorders

Study sections:
1989 NIH Special Grants Division, ad hoc review committee 1987-1989 American Heart Assn, Northeast Ohio Affiliate (ad hoc) 1989 NIH Special Grants Division, ad hoc review committee 1995 NIH Special Grants Division, ad hoc review committee

Committees:
National:
2001 - Clinical Genetics Examination Committee, American Board of Medical Genetics

School of Medicine:
1982 School of Medicine Task Force on Genetics 1985 - 1989 Co-coordinator, Area of Concentration in Human Genetics 1989 - Coordinator, Area of Concentration in Human Genetics 1999 - Committee on Students

Department:
1983 Search committee for Chief, Division of Pediatric Hematology 1994 Ad hoc committee on graduate education 1995 - 1997 Committee on Appointments and Promotion 1995 - Coordinator, Clinical Genetics Grand Rounds
Hospital:
1986 - 1992 Co-organizer and member, Disorders of sexual development team 1987 - 1994 Co-director, Center for Inherited Disorders of Energy Metabolism 1994 - Center for Inherited Disorders of Energy Metabolism 1994 - Director, Gaucher Disease Treatment Center 1994 - Director, Huntington Disease Testing Center 1995 - 1997 Liver transplantation committee 1996 - Director, Biochemical Genetics Training Program 1996 - Laboratory Liaison Committee 1997 - Director, Neurogenetics Clinic 1999 - Co-Director, Metabolism Clinic

Community:
1997 - Medical Advisory Board, Huntington Disease Society of America, NE Ohio chapter 2000 - Ad hoc committee on newborn screening, Ohio Department of Health

Teaching Activities:
Courses:
1982 - Human Genetics Committee (Phase 1 Medical Students), 7-10 hrs per year 1996 - Biochemistry Committee (Phase 1 Medical Students), 2 hrs/year 1996 - Genetics and the Law (Medical, Law and Ethics Students), 2 hrs/year 1998 - Advanced Medical Genetics 527 (Biochemical Genetics), 32 hrs/year 2000 - Advanced Medical Genetics 527 (Biochemical Genetics), 32 hrs/year

Postgraduate Training:

Sean Phipps, B.S.
Ph.D. Thesis committee, 7/84 - 6/86
Vickie Zurcher, M.D.
Genetics resident, clinical training, 7/87 - 6/89
Mark Johnson, B.A.
Ph.D. Thesis committee, 7/90 - 6/96
Meral Gunay, M.D.
Genetics resident, clinical training, 7/96 - 6/99
David Everman, M.D. Genetics resident, clinical training, 7/97 - 6/00
Derek Neilson, M.D.
Genetics resident, clinical training, 7/99 -
Mark Johnson, M.D., Ph.D.
Genetics resident, clinical training, 7/99 -
Linda Jeng, M.D., Ph.D.
Genetics resident, clinical training, 7/99 -
Khusroo Qureshi, M.D.
Genetics resident, clinical training, 7/99 - 6/01
Jeanne Brunger, B.S.
M.S. Thesis Committee member, 6/99 ­ 6/00
Marni Falk, M.D.
Genetics resident, clinical training, 7/00 -
Rocio Tarvin, M.D.
Genetics resident, clinical training, 7/00 -

Previous grant support:

1. A multinuclear NMR study of animal models of propionic acidemia and methylmalonic acidemia (AB Zinn, PI). Research Initiation Grant, Board of Trustees, Rainbow Babies and Childrens Hospital. Award for $10,000 (total direct costs). July, 1983 - June, 1985.

2. Biochemical studies of defects in the electron transport chain in mitochondrial myopathies (AB Zinn, PI). Robert J. Frackelton Fund, University Hospitals of Cleveland. Award for $10,000 (total direct costs). July, 1985 - June, 1987.

3. Complementation analysis of respiratory chain defects in patients with early-onset dementia (AB Zinn, PI). Alzheimer Center Pilot Grants, University Hospitals of Cleveland. Award of $10,000 (total direct costs). July, 1987 - June, 1988.

4. Complementation analysis of mitochondrial cardiomyopathy (AB Zinn, PI). American Heart Association, Northeast Ohio Affiliate. Award of $17,047 (total direct costs). July, 1987 - June, 1988.

5. Center for Disorders of Energy Metabolism (DS Kerr, Director; AB Zinn, Co-director), Rainbow Babies and Childrens Hospital Center of Care Grant. Award of $72,280 (total direct costs). January, 1989 - December, 1991. Percent effort: 10%.

6. Center for Disorders of Energy Metabolism (DS Kerr, Director; AB Zinn, Co-director), Bureau of Maternal and Child Health. Award of $747,112 (total direct costs). October, 1988 - October, 1993. Percent effort: 10%.

7. Ethics, Genetics, and Alzheimer Disease (Post SG, PI). NIH. Award of 155,377 (total direct costs). April, 1995 - September, 1996. Percent effort: 10%.


Current grant support:
Comprehensive Genetic Services in Northeastern Ohio, Ohio Department of Health #525K5 (HF Willard, PI). January 1, 2002 - December 31, 2002. Award of $194,000 (total direct costs). Percent effort: 50%.


Selected Publications

Ross JL, Stefanatos GA, Kushner H, Zinn A, Bondy C, Roeltgen D. (2002)
Persistent cognitive deficits in adult women with Turner syndrome.
Neurology;58(2):218-25
See PubMed abstract

Rosen CA, Murry T, Zinn A, Zullo T, Sonbolian M. (2000)
Voice handicap index change following treatment of voice disorders.
J Voice;14(4):619-23
See PubMed abstract

Ross J, Zinn A, McCauley E. (2000)
Neurodevelopmental and psychosocial aspects of Turner syndrome.
Ment Retard Dev Disabil Res Rev.;6(2):135-41
See PubMed abstract